Wounding Caenorhabditis elegans with Glass Wool

DANSing with Caenorhabditis elegans.

T he emergence of natural product research over the past decades has largely been driven by the discovery of biologically active metabolites for drug discovery programs (1). A broad array of organisms, including bacteria and fungi, and plants and animals have provided such important antibiotics as erythromycin, tetracycline and the penicillins, anticancer agents such as doxorubicin, mitomycin C...

Caenorhabditis Elegans

Transparent, free-living nematode worm. Unsegmented body plan with full set of differentiated tissues (neural, endoderm, ectoderm and muscle). Genome size approximately 97 Mb, as five autosomes and one X sex chromosome. Fully sequenced genome, which comprises approximately 20 000 predicted genes. Defined cell lineage. Has made major contribution to studies of development, cell-to-cell signallin...

Caenorhabditis elegans

The complete structure of the anterior sensory nervous system of the small nematode C . elegans has been determined by reconstruction from serial section electronmicrographs. There are 58 neurons in the tip of the head. Fiftytwo of these are arranged in sensilla. These include six inner labial sensilla, six outer labial sensilla, four cephalic sensilla and two amphids. Each sensillum consists o...

Measurement of sound propagation in glass wool

Straightening Caenorhabditis elegans images

MOTIVATION Caenorhabditis elegans, a roundworm found in soil, is a widely studied model organism with about 1000 cells in the adult. Producing high-resolution fluorescence images of C.elegans to reveal biological insights is becoming routine, motivating the development of advanced computational tools for analyzing the resulting image stacks. For example, worm bodies usually curve significantly ...